N-of-1- Our Call for Papers

September 14, 2016

We recently announced that we’re collaborating several other editors to edit a special “focus theme” on N-of-1 experiments for the established informatics journal, Methods of Information in Medicine.

N-of-1 Call For Papers (PDF)

Here’s an extract from our justification for the call:

Scientific progress in medicine and public health during the last century has been dominated by studies performed with groups of people. Today many people collect data their own data to help investigate a health problem, make progress towards a goal, or simply because we are curious. Such investigations need not be conducted on groups. Often, they involve just a single person who is both the subject and the investigator. They are “N-of-1” trials, where data are generated by the individual, normally making use of self-quantification systems, including mobile apps and portable monitoring devices. This focus theme of “Methods of Information in Medicine” on single subject research encourages submission of original articles describing data processing and research methods using a “N-of-1” design where the questions and analysis are guided by the interests and participation of the subject. We encourage submissions that focus on challenges and questions involving data collection, processing, integration, analysis and visualization in the context of single subject research. 

AREAS OF FOCUS MAY INCLUDE, BUT ARE NOT LIMITED TO: 

Personal health and well-being * Chronic disease management * Mental health * Autonomous self-experimentation in the context of health and well-being * Health education and autodidactic learning * Privacy, ethics and regulation issues 

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An N-of-1 experiment helps a physician identify the trigger of painful swallowing.

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Dr. Alexander Smith found the trigger of his throat pain by eliminating a likely culprit from his diet: dairy. He noted that the pain disappeared, and then reintroducing the offending food and noticing that the pain came back. This simple protocol substituted for a much more difficult process that is typically recommended, saving him a lot of time, stress, and money.

What did you learn?

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We've posted more than thirty new Show&Tell videos from our conference in Portland, including Professor Allen Neuringer's remarkable opening talk about what he's learned from thirty years of doing and teaching self-experimentation.